Lynne Dawkins Senior Lecturer in Psychology, University of East London, Stratford
Olivia Corcoran Reader in Bioanalytic Chemistry, University of East London
Abstract
Electronic cigarettes (EC) are battery operated devices that deliver nicotine via inhaled vapour. Two previous studies with naïve users concluded that ECs deliver little or no nicotine. A more recent study however, using experienced EC users, reported a significant increase in blood nicotine delivery. The aim of this study was to explore the subjective effects and profile of nicotine delivery in regular EC (‘skycig’) users. 15 regular users (3 women) completed a 3 hour session using a new boxed skycig fitted with an 18mg/ml crown tobacco gold cartridge.
Following overnight abstinence from nicotine/tobacco, participants completed 3 phases: 10 puffs, 1 hour ad lib puffing, and 1 hour rest period. During each phase, blood was taken and questionnaires completed to assess subjective effects. There was a statistically significant increase in plasma nicotine levels from baseline to each and every follow up time point but with considerable variation between participants. Decreased ratings of urge to smoke and nicotine withdrawal symptoms were observed and few adverse effects were reported.
These findings demonstrate effective nicotine delivery after acute administration using the 18mg skycig in regular users and further suggest that experienced use and the manner of use may influence nicotine delivery.
Source of funding: SKYCIGS
Declaration of interest: This study was funded by SKYCIGS. The company had no input into the design or conduct of the study.
